SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5304b0bf41c7edf365534022cf6fe7d2f0faabddb549d8293502727c7bf6af4' 
  AND token = 'hZrQD/puI1trhua5AhMDG2+5xRN+iFzqOy6fZfQ7nnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}