SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25978918c4edb397c3f6d870597c0344e060b0ea961bf554a0a262647e25df6e' 
  AND token = 'Fv91Q76zhz8rrdev1uZNGHZfBTj34Cr5G5+eiP/Q8WA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}