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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e503f6705f37e580f4dbd772c8afaffbf3d6f2d5b99ef27eaabe52f228d266d9' 
  AND token = 'RNW4H4JcSiKCgDI4GYT7YjCdilWmOKLgFUNbMw4nBuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}