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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c24c5b8018c3a45907d937686be4a8cb84e113071bec96e6bb7b194f26dcfc6f' 
  AND token = '0ZtAHsNlRGQQLEnOOT7HtiXSeLth31AY+pXjszvpsqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}