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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7248d249b4c6c173dd7c9e5403b12e4e31d8eba2cf23e0284c2d06a65f0971f' 
  AND token = 'PPfYCQ502fvJL35qZuxO4nQlcl+oeY2NuIKC/WfW+9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}