SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d1b686eac2d58d186a17825ff6311e515bc2ec92dbca10cdc2758535c3e0c9f' 
  AND token = 'UaMWfo4HYEqp45f4nXyvB+zYHPKQ5oQlIz/qufm6MzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}