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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e9750641d7a942be52d58b06f3f7ed53252d9ff6f5e8328abc31dfd85901e0b' 
  AND token = 'W7JLysoSIK2MQvxr83eIIQPbKh7csGlh+eRhXtPHd7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}