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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3166c97ed029adf4c33e5f48b7f78b8f1bfc961a10d1342ec91add6d024752ef' 
  AND token = 'nAJfy9tmtBdTnX02fNwl5aWoV8BdwQDDrnLqR0BpsWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}