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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2441441d3d813fa6d3a5c263c292695442568406dba675fc552237b58c622722' 
  AND token = 'IwCKXoPQYupnEXyp/Z+Uwaeem+jE/n2pz75dnHquR+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}