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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63fb2a481aef723a7e06af8fc7d0bf3a7c364ae815eb5725a8af6d7943396c1b' 
  AND token = 'RpQMD3Tek1kpWk/8XWdrmc7ZYmQ79M3hN9TVZcFipTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}