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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5371029450a60e43b565b4284bdb78fa83e5a3a3bb3763561226b03ee05d94f' 
  AND token = 'IRR/OtRYTg5VD42vsh444FnwZmHzdYNHV/r5SG61teU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}