SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e6c79434bb11b54e937f04ba990dafec80f438e404909f03bebfde9920f9fc5' 
  AND token = 'I6wc/pt6D4Fj1z9K/8Uos9U6lKgoVFU93uKx625vRqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}