SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd603b10c66d4b0e4062089513197ddfc85f09ae8359cf4fc25ede5884375a886' 
  AND token = '2HJX71XGRwjeS3VmF5a2tEMD96K92DQXVSucS8i/SAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}