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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb3549b250d16c4fca3a92fcd4e5e4b351c864b4e3481f366c3ef8b5b04d1c20' 
  AND token = 'JJkPINJYyzSK29N7106ieVSorL264kAy3OA30XPJTrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}