SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '537252ba0aa57fef4bff960e8271dd5f78ee6a910ce91f9d2a15e33ee7c11d06' 
  AND token = '/NkYnZneutwsxVJPuGV/ul07UEi0EY9EoVwBXcZz9RY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}