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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e265187fd8ecde69451b6f66f640e88aa52849956478c7bdb9a906b53808d1fc' 
  AND token = 'lMJLVaSigaCT3mKwt9TrZMyieeEQw22zNsLBpToCA0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}