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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6fec37b765e33881e51a5f0766087b3efa2580b251bcf22da3aad9b7a059b9d' 
  AND token = 'p+ika/STTVft3W1BcduZ/xpZCubD4qfF89pYVbbVJ3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}