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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2153ad80dc3281ce3ea3842dc1ea30a6a7a8f5e5b297c00d2b32f06427203603' 
  AND token = 'cVjKTd8t3YEsq6uj9LkTvvxR4L7pnNmuCAD0iiytgZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}