SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cb8c8bc5bacfd698afd4d420409dc83cf502863b8295e3738ac6fe7a094e7da' 
  AND token = 'b2x1poNGyJKM6B++rZfPr3GSk0K1aRfLNukeUGPhSb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}