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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f8a85ee4e8ff4859ecf852902bd75483951f686c5f103661a1bb8cd84563a27' 
  AND token = '5C63sGGjUBzRX0Gm/6XGqFLJcPi+xm95rbak0S76qGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}