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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38d0b0c526331d18946350efac8d6f06b9b6abba5e22b26fbe5180f86ef70621' 
  AND token = 'JFscukOzkgX0TKmKSmWNWnVSWIdFNmqOhe1OzQpbLGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}