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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d65c1c31d975f47e7502f2c94dd3d248c8f3760e2aa38e114d86a97bf1b782b' 
  AND token = '2uc/nB0GW1ceU1x8dwYnwcjydoz/lViCYdnOrn4BdP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}