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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82aa06ab737cd54771605039008ec886da57bb01a583294d4e316406d1a3d019' 
  AND token = '5lcO4jetkHEbGl84fziovoWwfFpiXxWV8MixGN7ic74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}