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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4288f679a25d8b42c5269dc6fc50c1661610c4d315e2ce37828b761765ba5a7d' 
  AND token = 'toxLZsybrhEJvkAGzeuaqnOmWVL4lkme93cn/9liq5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}