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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3c3413d53272f356d6293050ce22008ae7b465a812f816e32f74e112732f4de' 
  AND token = 'IL123tj7tIBINJUEPd6fJU7ik6aa//vGsuK4RCZeEjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}