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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0236d11a73b76da475dbd4be03376f23e106ec70b66ed0a0da8667ec1976f8f7' 
  AND token = 'JXkjH9Hf5CXLwAVzIBUBh4hxhGa6dnxJU9XkfpgFvjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}