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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42b7c1ed63fcab26361a1e9303395488f3ee50cde6193532c0e61473952741e' 
  AND token = '00xeMcdswZlZMUPnWU9BVux82H3RfQUshRu6a5DU2Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}