SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6688e0e47e70132cf553175dc59553d7dfb25840afd5ed15800858f1405908a2' 
  AND token = 'tvLLD8OHMnHQG1WcSRz31F443MeNh719/I3KW596SC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}