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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f49bd04ff1ac321d18fd103624064faae044eeedf7f57b32ac20d63a81e146b' 
  AND token = 'dPW0bwtW38HfAwDA1LTK/EV599nYqUybCizDr9rAoJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}