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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80a42f16ee4da2dda9f542a3a6ec487660e45311a5548357cc2e17286b10c10c' 
  AND token = 'TWYjSCI2gLzyu8I0YKoyTjwo+GazYcf4eOPRfkfbYBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}