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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2127f6c14cfec7773e18efef0d7872df719e5063db00c9d5fc08b4b32c92aa9' 
  AND token = 'RhDMjSakEmEZhG5+wUtDz+6g6V5e7GIWKW24AzXdtMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}