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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b446d49313e53247b386a4c3711921b06f477c1ec915a967e1e7c2a6fd5e2a4a' 
  AND token = 'pBs6MfEKmrHwCioGc0MTeYSlrqf2HS7AF+zMPP6VNO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}