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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '345d5f4e91d76df1d708e23e59d2b9a29a8eda2a270c33d5ed0b7f5641bda570' 
  AND token = 'H149FkQnHGd5bHFWvqWf23YyuUVUvkOTv7kr2BWdewc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}