SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c103d6629818ae3b66c46c61c5ea01e9b3eb84ad5b005033645b9e77f64d2a11' 
  AND token = 'MT+ulylzKZ8Q4Q+BlrNpnzgFYFR5DODjW4Nuh4lINaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}