SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d8d1a94b864f84afd8bb1450d062b6afbb50a6f3a94a745a9e87a07647e1396' 
  AND token = 'nIm688Wiw9O0S4TsuiEuHoyVELMcPTqzZgMZ/+W0+gA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}