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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4102af40613acf20b9f1f4fad22a5be209999cd1c16920064cf893b94ec5e0c0' 
  AND token = 'jjoPvtIpQRIXPDRuWbZrRFK6sHAS4BPIJ6bvMpbTZfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}