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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fc26f564e5cba10c4717eb686a0a5dcb45f26c3579155fe02255f7f0d8c0977' 
  AND token = 'X0BSENTK8Vg3lVFbeRBXk5qfl88+uPpBQdrBYjlfwvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}