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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff8fab72a5d987204ac08229385a08d6020a5c3d24cf2e2219f7d7b57f65a999' 
  AND token = 'IHPfOa70yOziEY7OgP0qBu4twc2qG1cNTwbv/e8Fgqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}