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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22dde3a33ecd4d7ef5793f713317d7f1a3f6f727ef1b6256ddccebc489d6ae5c' 
  AND token = '6X2uBRq5ng/QGorbVXcUIzK14S6+TVSj+OO4R6jz+Fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}