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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32fa3cb1e935aa35207c85621abe1f607f9f0d1857f5063b086204dea3673ada' 
  AND token = 'CahR0c/rUlQYuZl2OVDPN1kj5YWDhs+bE8EmZmYPGjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}