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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00b1e7d4e86236e07f13e08b05a28b75f60c922781fb8abf451a778f7e931ed3' 
  AND token = 'DMqcNWYk/yO+pHMZPi67itgoPq9zsEfYtEb9UzIEl3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}