SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72677c4f90029f7aa2258d67a131b514ccab7706742af21e2713538842e63a3d' 
  AND token = 'f4YbnkT/KqIRLy5WNmOPnxBNbSRY7+07j+VB6yRI+XE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}