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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64c5060109f96354b6b6a53827d9f7c180125c59b8bc829ee4bdc86ec628288d' 
  AND token = 'Hjlw6X1O9fpQNSXlpelCJPjIGPejRKHRC6ffC8MSM5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}