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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce6dcacd2b3d1605f2f671621feae9ff8f97bed8672b4b2cdd4414f20025bab9' 
  AND token = 'UJJHT9oEyTaEAO/B3T+TwhfzXvk8W57zGkrCT5WH7MM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}