SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f86378439d257288f7b4fbe05684d8a3bd48c6fb03c4f58969af69fc4479c3a7' 
  AND token = '9Me267cnQBZYPpI+LxPAFGR/aYRb1i+lshqxLofJtEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}