SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cf363f1084fb0d567f59dddc1e679e54fa87d02dfc720a6a45daaadef8dedd4' 
  AND token = '8kBmpBT/KewnqzLWEkiV3cGNn3Ts2S5yGTurkrSH6FU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00083

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}