SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1294d6be22adf7c149c5d6e3b917709f5ae9a7e2f263210ea16a780c669748cb' 
  AND token = 'jYal6lUE0GgbedylK06qzBV7beFb5jNyvWdsc3KP4dY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}