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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea2dd0c36633d76d5b904a369b2b496aba641049889b292d4a8b5d1c18c27a90' 
  AND token = 'Rgyti4zdR4nlHp8T6CWFUlxAjdd2oCpoPfLQ0I81qO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}