SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e47d7251eabc815eacc7660ff2a293df18926d8321743c251eeae57559b044e2' 
  AND token = '6IrcfedM1e0XxhpJjR9TVfLO39W2TM46aS4bBqUT2gQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}