SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b67987db8dafea3679a7bd81cc076f94aba1804a8b8c267e14c931a5eb08551' 
  AND token = 'IcN71Qum/d289tQlXwxmAxdYO3L/5lDVRhT5Jpce1NI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}